Stanford RNA 3D Folding

Overview

This competition challenges you to predict the 3D structure of RNA molecules solely from their sequences, a critical step in understanding biological processes and advancing medicine. You will develop machine learning models to tackle this complex problem, building upon recent breakthroughs in RNA structure prediction. Your work can lead to more effective treatments and a deeper understanding of RNA's role in biology.

Requirements

Teams can be any size, but you must accept the competition rules by May 22, 2025, and the team merger deadline is also May 22, 2025. Submissions must be made through Kaggle Notebooks that run within 8 hours on CPU or GPU and have internet access disabled. You can use publicly available external data and pre-trained models. Your submission needs to be a CSV file named 'submission.csv' containing the x, y, z coordinates for five predicted structures (structures 1 to 5) for each residue's C1' atom, for every sequence in the test set.

Prizes

The competition offers $75,000 in prizes. The top three teams will receive cash awards: 1st place gets $45,000, 2nd place receives $15,000, and 3rd place gets $10,000. Additionally, there are Early Sharing Prizes of $2,500 for the first two teams to publish a public notebook that scores above the benchmark on the leaderboard after a data refresh.